an investigation of drug interactions in hospital pharmacy prescriptions
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abstract
drug therapy is a complex and important process and because of the importance of drug interactions, especially in in-patients, accompanying problems and obstacles would exist as a result of concomitant use of drugs in these patients. for this purpose 3130 prescription order forms from bou-ali hospital were collected and all potential drug interactions presentwere extracted and evaluated in terms of significance, severity, documentation and onset. interactions were divided into 5 groups based on their significance, with group 1 being the most important and group 5 the least important. most interactions observed belonged to groups 4 and 5, accounting for 68.5% of all interactions.group 1 interactions only accounted for 7.8% of all interactions observed. when considering the onset of interactions, the most dominant type (55.8% of all interactions) were the slow-occurring ones. in terms of the severity, most interactions (47.2%) were of the medium (moderate) type. strong (severe) interactions only accounted for 8.2% of all interactions. finally, in terms of the documentation of interactions, the most prevalent type were the probable ones, accounting for 56.8% of all interactions observed. definite interactions only accounted for 4.3% of all interactions.
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Journal title:
iranian journal of pharmaceutical researchجلد ۲۰۰۲، شماره ۱، صفحات ۱۵-۱۹
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